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KMID : 0358420170600060602
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Korean Journal of Obstetrics and Gynecology
2017 Volume.60 No. 6 p.602 ~ p.607
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Peptide YY producing strumal carcinoid tumor of the ovary in a postmenopausal woman: a rare cause of chronic constipation
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Noh Hye-Kyung
Kwon Byung-Su
Kim Yoon-Hwa
Lee Nam-Kyung
Choi Kyung-Un
Suh Dong-Soo
Lee Dong-Hyung
Kim Ki-Hyung
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Abstract
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Strumal carcinoid tumor of the ovary is a rare subtype of ovarian carcinoid tumors; it is characterized by an intimate mixture of thyroid and carcinoid tissues. We present a case of a 64-year-old woman who presented with the chief complaint of persistent, severe constipation for over 5 years; she was later found to have an ovarian strumal carcinoid tumor. Computed tomography showed a well-defined solid mass measuring 6.4 cm at the right adnexa. The patient underwent right salpingo-oophorectomy and was histopathologically diagnosed as having a strumal carcinoid tumor. Immunohistochemical examination showed immunoreactivity for peptide YY (PYY), which exerts an inhibitory effect on the peristaltic actions of the distal intestine. After surgery, the patient's constipation resolved rapidly, suggesting a correlation between PYY producing ovarian carcinoid tumor and constipation. This is the first case report of PYY producing primary strumal carcinoid tumor of the ovary associated with persistent, severe constipation from Korea.
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KEYWORD
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Strumal carcinoid tumor, Peptide YY, Constipation
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